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Labstract Courses

NMR for Medicinal Chemists





Audience
Scientists wishing to improve their knowledge of NMR and to better understand its use in structural confirmation/elucidation, particularly in drug discovery.

 
 Duration A one day course.     
 Objectives This one-day course starts by covering the basic elements of 1-dimensional NMR techniques in medicinal chemistry including chemical shift, J-couplings between nuclei, structural information from coupling constants, second order effects, intensity & integration. All topics are presented with reference to drug-like molecules and precursors. The course then moves on to cover more advanced techniques such as homo- and heteronuclear 2-dimensional experiments, through space interactions, the nOe effect and magnetic non-equivalence. The course concludes with a worked-through case study and a group problem-solving session. Practical aspects of spectroscopy including sample preparation and basic shimming techniques are also covered.    
Training provided by



Please get in touch with the training provider at info@labstract.co.uk, 0870 8032491 for availability and costs.

www.labstract.co.uk

Practical Flow Chemistry





Audience
Anyone in industry or academia wishing to learn more about the emergence and practicalities of flow chemistry.

 
 Duration A one day course.    
 Objectives An introduction to the principles of flow chemistry delivered by Dr Andrew Mansfield, Flow Chemistry Solutions. How and when to apply the technique with pertinent illustrative examples of chemistry & equipment, followed by a tutorial/workshop covering batch to flow conversion and troubleshooting with worked examples. Finishing with a practical demonstration session on commercial flow chemistry apparatus.    
Training provided by



Please get in touch with the training provider at info@labstract.co.uk, 0870 8032491 for availability and costs.

www.labstract.co.uk

Practical Medicinal Chemistry





Audience
Scientists in the early stages of their career in medicinal chemistry and Graduates, PhD students & Post Docs considering a career involving practical medicinal chemistry.

 
 Duration A one day course.     
 Objectives A hands-on laboratory based course delivered by Dr Suki Klair, Labstract Ltd, covering a range of practical techniques encountered in a modern medicinal chemistry laboratory. Starts with an introduction to laboratory safety, good notebook keeping and how to simplify synthetic calculations. The course moves on to reaction set up, including handling solids, liquids & air-sensitive reagents, followed by reaction monitoring, work-up techniques, purification and analysis. Delegates will perform reactions involving modern techniques such as microwave chemistry, solid-phase extraction and the use of automated chromatography systems, all of which are now commonplace in industrial laboratories.    
Training provided by



Please get in touch with the training provider at info@labstract.co.uk, 0870 8032491 for availability and costs.

www.labstract.co.uk