News

Macomics Unveils its Lead First-in-Class Anti-Pan-LILRB Monoclonal Antibody Programme with Positive Pre-clinical Data Presented at AACR 2024


• Macomics’ lead programme, MACO-355, in IND enabling studies is a ligand-blocking independent pan-LILR monoclonal antibody for the treatment of cancer

• Data presented at AACR 2024 shows MACO-355 is highly potent in macrophage reprogramming under tumour-like immune suppressed conditions

• Data demonstrated Macomics’ ENIGMAC™ platform at-scale CRISPR screening for macrophage target discovery

Access to compound collection enables greater flexibility and efficiencies in screening and target identification

Cambridge, UK and Kyiv, Ukraine, 11th April 2024: Metrion Biosciences Limited (“Metrion”), the specialist ion channel and cardiac safety screening contract research organisation (CRO) and drug discovery company, and Enamine Ltd (“Enamine”), the global leader in supplying small molecules and early drug discovery services, announced that Metrion has enhanced its High Throughput Screening (HTS) services with the addition of access to Enamine’s compound libraries.

Read April's eNews 


Growing Opportunities for our Network, featuring:


✅ Welcome from Tony Jones, CEO, One Nucleus


✅ Review of this year's BLSA (Building Life Science Adventures)


✅ Tony Jones reviews our Inaugural Annual Awards 


✅ Boston Bootcamp Winners and What they Can Look Forward To

Regulatory Compliant Tissue Microarrays


AMSBIO reports that its extensive range of FDA tissue microarrays reliably enhances tissue cross-reactivity (TCR) and other target validation studies.


These high-quality tissue microarrays (TMAs) enable high-throughput analysis of a panel of tissue types recognized by the Food and Drug Administration (FDA) and the European Medicines Agency (EMA).

Astex Pharmaceuticals Announce Key Data Presentations at the American Association For Cancer Research (AACR) 2024 Annual Meeting

 
As technologies emerge that enable a wide range of naturally occurring medicinal compounds to be reproduced by a host plant within a controlled environment, is it time to review the use of plants as biofactories? Innovation facilitators Agri-TechE are partnering with the life-sciences network OneNucleus to explore the market potential of using plant factories to mass produce rare drugs. Find out more about the event here

Laverock Therapeutics announces appointment of Ali Elsley as Finance Director and expansion of team


Stevenage, UK, 26 March 2024 - Laverock Therapeutics, a gene-silencing company with a uniquely powerful technology for the development of programmable advanced therapies to tackle major diseases, today announces the appointment of Ali Elsley as Finance Director.

• Leading precision medicine and nucleic acid therapy (NAT) innovators will harness their platforms to develop NAT drug candidates for novel gene targets with strong genetic association to sporadic ALS

• The programme will be supported by mechanism-based patient stratification biomarkers to identify likely responders and accelerate and derisk clinical development

Norwich Research Park showcased its latest collaborations with industry at its Enterprise Tuesday event held on Tuesday 5 March at the John Innes Conference Centre.

Cancer Research Horizons, the innovation arm of Cancer Research UK, has announced the winners of its second Innovation & Entrepreneurship Awards.

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