Computational Chemist

Domainex has one position available for an experienced computational chemist during an exciting time as a we embark upon significant enhancement of our CADD capabilities. The ideal candidate will be qualified to PhD level or a B.Sc/M.Sc. degree in a life science and be highly-skilled in small-molecule and protein modelling and chemoinformatics approaches applicable to drug discovery. Experience in an industrial drug-discovery setting is strongly preferred. Applicants should have hands on experience of applying a wide range of computational tools and techniques, including structure based and ligand-based design and virtual screening. This role will operate a cross-discipline matrix environment and a knowledge of drug discovery processes and appreciation of key concepts from collaborating disciplines such as medicinal chemistry and biophysics is essential.
Main Roles and Responsibilities
• Application of problem-solving ability through a combination of personal knowledge of computational techniques with the desire to seek-out and apply novel and innovative solutions from the wider literature to help progress customer projects
• Run virtual screening (both structure and ligand-based) and select compounds for purchase
• Support on-going hit discovery and lead-optimisation projects
• Influence and aid the further development of our computational chemistry and capabilities
• Work alongside the business development team to identify and secure new opportunities and contribute to the preparation of scientific proposals