Senior Research Assistant - Cellular generation and phenotyping

A rare opportunity has arisen for an experienced cell and molecular biology specialist to join Cellular generation and phenotyping (CGaP) team as a Senior Research Assistant, to support the expansion and diversification of our Functional Genomic platform, with the aim of expanding into new challenging models e.g. iPSCs organoids, primary cells and technologies such as CRISPRi and Saturation Genome Editing.

Do you thrive in a multi-disciplinary team, working together to solve complex cell biology issues?
Have you ever worked in a R&D, high throughput or process driven setting?
Do you have experience in functional genomics or CRISPR technologies?
If you said yes to the above questions, then this is the job for you.

About the role:

You will play a fundamental role in developing and scaling functional genomics protocols. Working in close collaboration with our partner faculty team you will help develop and transfer protocols into the Cellular Operations facility.
You will be working as part of a cross functional group using advanced gene editing technologies such as CRISPR to deliver functional genomics projects in partnership with faculty teams.

You will be working with an experienced team of enthusiastic, highly motivated research assistants, under the management of a Senior Scientific Manager.
Your role will include offering day to day support to the team including, training, troubleshooting and identifying areas for process improvement.
A fundamental aspect of the role will be to inspire, develop and mentor junior staff, as well as working closely with the Senior Scientific Managers to successfully deliver projects.
About the team:

Cellular Operations are a core division responsible for providing cell biology and gene editing resource and expertise to the wider institute. We do this by running multiple, diverse projects for various faculty teams from across the Sanger Institute. Our two departments, Cellular Generation and Phenotyping (CGaP) and Gene Editing undertake a portfolio of projects that includes CRISPR screening, iPSC derivation and differentiation and genetic manipulation, organoid derivation and the Human Cell Atlas.

As a department we strive to work together where possible, building a culture of continues process improvements. We encourage all staff to take part in department and institute wide initiatives.

Essential Skills
BSc in Biology plus extensive cell and molecular biology laboratory experience
Prior experience of running, developing and scaling cell based assays and processes, including cell culture systems, reporter assays, cloning, flow cytometry, ICC, PCR, etc.
Ability to troubleshoot complicated laboratory processes
Experience of identifying and successfully resolving complex scientific/technical issues
Proven track record in generating and analysing high quality data
High attention to detail and good record keeping
Proven ability to be able to organise and schedule their own work
Proven experience in training and developing others in scientific techniques
Excellent communication skills
Experience in collaborating with others and effectively working in teams
Ideal Skills
Significant experience in functional genomics and CRISPR based screening technologies
Proven ability to be able to organise and schedule the work of others
Prior experience of working in a containment level 2 laboratory
Other information
Full time, part time and flexible working applications considered.

Application Process:

Please apply with your CV and a cover letter outlining your suitability for the role using the criteria set out above and in the job description.

Closing date: 11th April 2021

Application Closing Date: 
11 April