Senior Scientists Medicinal Chemistry

Company Description

Sosei Group Corporation (trading as Sosei Heptares) is a research-focused biotechnology group, publicly listed in Japan (TSE: 4565) and with sites in Tokyo, London and Cambridge (UK).

Our mission is to make a significant contribution to improving the quality of life and health of people around the world. To achieve this, we will discover, design and develop the most innovative and effective medicines for patients worldwide, through our world-leading patent-protected technology and platform.

Our primary focus is the discovery, design and development of new medicines originating from its proprietary G Protein-Coupled Receptor (GPCR) targeted StaR® technology and Structure Based Drug Design (SBDD) platform capabilities. The company is advancing a broad and deep pipeline of partnered and in-house drug candidates in multiple therapeutic areas including neurology, immuno-oncology, gastroenterology, inflammation and other rare/specialty diseases. Its leading clinical programs include partnered candidates aimed at the symptomatic treatment of Alzheimer’s disease (with Allergan) and next generation immuno-oncology approaches to treat cancer (with AstraZeneca). Our additional partners and collaborators include Novartis, Pfizer, Daiichi-Sankyo, PeptiDream, Kymab and MorphoSys.

Sosei Heptares has approximately 145 employees based at its new R&D research facility at Granta Park.
The size of the company ensures a transparent linkage between all activities from early discovery through to clinical development.

Position

We have opportunities for experienced medicinal chemists to join our medicinal chemistry team as Senior Scientists among our permanent staff.
For the right candidates, the roles provide an excellent opportunity to join an industry-leading drug discovery company and to impact research projects in our unique environment of structurally enabled GPCR drug discovery.
Requirements

We are seeking candidates whose profile will include:
• A minimum 2.1 degree (or equivalent), a PhD in Organic Chemistry preferable but not essential
• A minimum of 5 years’ experience in the pharmaceutical industry - working in small molecule drug discovery projects
• A demonstrable track record of impact on drug discovery projects, through both molecule design and synthesis
• High level understanding of organic synthesis and ability to apply such understanding in a practical setting
• Understanding and application of state-of-the-art medicinal chemistry practice
• Strong analytical and problem-solving skills, and ability for lateral thinking.
• Enthusiasm and motivation for drug discovery
• Highly effective working in team environments and ability to work effectively independently.
• Excellent communication and interpersonal skills and demonstrated capability to operate in an entrepreneurial environment.
• Ability to communicate clearly, both verbally and in written reports, in English.