Bioinformatics Scientist - Algorithm & Assay Development

Company Description

We are a leader in liquid biopsy. Every day we transform the lives of cancer patients and their families through the power of liquid biopsy. Our tests unlock essential genomic information from a simple blood test and allow clinicians to make more informed treatment decisions for their patients.

We are dynamic and innovative, focused on the development of new ground-breaking technologies in a fast-paced and international setting. Our exceptional team of talented and driven individuals work together to combine their energy and expertise in world-class research, product development and commercialization to bring new tests to the patients that need them.

If making a difference is in your DNA and you are ready to join the liquid biopsy revolution, then you could be just the person we are looking for to join our team based in Cambridge, UK!


Role Overview:

This role involves optimising and streamlining our InVision analysis pipeline while also working with the assay development team to build novel methods and contribute to the design and creation of new products. This position offers the exciting opportunity to work at the frontier of cancer diagnostics while seeing the entire product development pipeline from concept, clinical validation, to commercial product. This role will involve the analysis of NGS cancer genomics data, biomarker development, innovative algorithm design and optimisation of Inivata's technology. We expect that applicants will have prior experience in the field of bioinformatics and a good understanding of NGS analysis, for example a MSc or PhD degree in a relevant field and/or industry experience.

Key Responsibilities:

Contribute to the development of novel methodologies and algorithms for the analysis of ctDNA.
Analyse, summarize and interpret NGS data sets using existing and customized approaches.
Contribute to technology development by providing insights into computational solutions and identifying suitable workflows.
Interpret the outcome of proof of concept experiments and help to improve the design jointly with the tech-dev team.
Develop production ready, regulatory compliant code in partnership with the software development team,
Support the rollout, optimisation and improve scalability of Inivata 's analysis pipelines
Provide support to clinical, business development and other departments for novel and existing products
HIPAA/GDPR Compliance: Position will

Agree to abide by Employment and Confidentiality Agreements and End User Policies
Commit to stay up to date on training requirements for HIPAA/GDPR
Understand the importance of the proper handling and disposal of ePHI and agrees to follow HIPAA/GDPR Regulations
Abide by the requirements for the proper disposal of equipment containing ePHI
Agree to report breaches and the improper handling of ePHI to the Company’s Privacy and Security Officers
Produce and adhere to proper validation documentation



PhD in the field of computational biology/bioinformatics/applied statistics, or significant experience in that space.

Experience with next generation sequence data analysis (Essential).
Experience in novel algorithm development, data mining and machine learning (Essential).
Scientific programming experience, using either R or Python (Essential).
Experience with variant calling, exome/WGS pipelines or other high-throughput genomics workflows (Desired).
Experience with cancer genomics or related data sets (e.g. epigenetics) (Desired).
Prior experience with work in a regulated environment, in particular for software and quality assurance, such as ISO 13485, EN 62304, ISO 15189, or other (Desired).
Excellent communication and presentation skills.

Application Instructions: 

Other information



Inivata Limited is based in Cambridge, UK.

No agencies please.

To Apply:

We look forward to reviewing your application!

Application Closing Date: 
07 March