Scientist / Principal Scientist

Discovery Bioscience Scientist/Principal Scientist

Location: Babraham Research Campus, Cambridge
Salary: Dependent on experience
Contract: Permanent and full time

Interviews will start as early as 1st October so early application is encouraged.

Cancer Research UK's Therapeutic Discovery Laboratories is the in-house CRUK drug discovery unit with a principal focus on establishing and prosecuting biologically-themed multi-project alliances with industry.  Based at the Babraham Research Campus, Cambridge, and the London Bioscience Innovation Centre, London, TDL comprises over 80 staff from both industrial and academic backgrounds.

We are currently recruiting for two positions, a Principal Scientist and a Scientist, to join CRUK-TDL’s Discovery Bioscience Screening and Compound Profiling team to prosecute high-throughput screening (HTS).

At CRUK-TDL, we bring together the best minds in basic and clinical cancer research, the rigour and drive of pharmaceutical and biotech companies, and our in-house drug discovery and alliance management capabilities to deliver breakthrough medicines for cancer patients

In recent years, we have established successful alliances with AstraZeneca, Teva Pharmaceuticals, FORMA Therapeutics, Merck KGaA, LifeArc and Celgene.  We have also been successful in implementing the alliance model through the formation of spin-out companies, including Artios and iOnctura.

Our laboratories house the personnel and equipment to progress projects from initial hypothesis through to selection of candidate drugs.  We couple this with a deep understanding of academic and industrial drivers enabling us to build alliances that satisfy the curiosity of basic research and the rigour of drug discovery.

Ref 10630a Principal Scientist: biochemical HTS
This position will focus on bringing scientific leadership to the design, prosecution and analysis of biochemical HTS screening in support of alliance objectives. Essential experience includes:

• Automation
• Analysing large data sets
• Working with small molecules is essential
• Detailed knowledge of biochemical assay technologies (eg fluorescence, fluorescence polarisation, FRET, luminescence).

This role would suit a BSc, MSc or PhD graduate, or someone with an equivalent level of experience, with significant experience of HTS in a drug discovery environment.

To see a full job description please click here.

Ref 10630b Scientist: biochemical HTS
This laboratory-based position will focus on delivering high quality biochemical HTS data to identify novel small molecules in support of alliance objectives. Essential experience includes:

• Automation
• Analysing large data sets
• Working with small molecules
• Basic knowledge of biochemical assay technologies (eg fluorescence, fluorescence polarisation, FRET, luminescence).

This role would suit a BSc, MSc or PhD graduate, or someone with an equivalent level of experience, with some experience of HTS in a drug discovery environment.

To see a full job description please click here.

The successful applicants will form an integral part of the CRUK-TDL team working alongside our industry and academic partners to progress novel cancer targets towards patient benefit. Both roles require:

• Excellent communication and interpersonal skills
• The ability to work well in a team
• Strong organisation skills and attention to detail

At CRUK we value diversity and we're committed to creating an inclusive culture where everyone is able to be themselves and to reach their full potential. We actively encourage applications from people of all backgrounds and cultures and believe that a diverse workforce will help us to beat cancer sooner.

Please note, from 2019, our head office will be relocating from Islington to a new office space in Stratford, close to the Olympic Park.