Astex Pharmaceuticals is a world leader in innovative drug discovery and development. The company has successfully applied its proprietary Fragment-Based Drug Discovery platform to generate multiple new drug candidates that are progressing in clinical development. Successful collaborations have led to three launched oncology drugs (Kisqali® partnered with Novartis, Balversa® partnered with Janssen and Truqap™ partnered with AstraZeneca). Astex continues to grow and focuses on Neurological Disorders and Oncology.

The Role

An exciting opportunity for a talented assay biologist in the drug discovery bioscience group at Astex, contributing to the drug discovery process from target evaluation to candidate selection. Working in multi-disciplinary teams with structural biologists, biophysicists, chemists, bioinformaticians and biologists, the successful candidates will have the opportunity to apply their knowledge of enzyme and protein mechanisms to optimise fragment hits to lead compounds. This role will involve developing and running primary assays to support the testing of compounds against relevant drug targets. Previous experience and knowledge of biochemical assays and screening formats are essential.