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For the long-term storage of biological samples at -80oC, historically there has only been one option: upright, mechanical compressor-based sample freezers. However nitrogen vapour freezers have arrived as an alternative, with no liquid nitrogen held within the freezer, these vary from the traditional cryogenic liquid nitrogen freezers. Whether the samples in question are stem cells, reproductive cells or other biological samples, every researcher will have their preferred storage method. But which is best?  What is the difference between nitrogen vapour and mechanical freezers?…