Cleveland​, UK, 29th April 2021 / Sciad Newswire / Leading UK peptide and antibody producers, Cambridge Research Biochemicals (CRB) have today signed a new distribution agreement with Fluoroprobes, LLC (FPL) and Click Chemistry Tools (CCT) to add FPL and CCT’s generic fluorescent activated dyes and click chemistry enabled click-reactive dyes to their existing service portfolio. The distribution agreement grants CRB the rights to market and sell the generic and improved Alexa Fluor-based DISCOVERY® Dyes both as part of their custom services, and with their catalogue peptide (DISCOVERY® Peptides) and antibody (DISCOVERY® Antibodies) services in the UK and Europe.

FPL and CCT’s dyes have improved chemistry compared to the Alexa Fluor dyes resulting in increased solubility as well as incorporating “click” chemistry compatibility. The “click” reaction involves coupling of an alkyne functionality to an azide moiety in a rapid and straightforward reaction. This builds on the existing licencing agreement between CRB and the Scripps Research Institute to use the “click” chemistry system.

This agreement also affords CRB the increased flexibility to offer larger quantities of labelled peptides at a more affordable price, opening up more options for scale-up to a wider range of customers.

CRB is a world leader with over 40 years' experience in providing complex and heavily modified peptides and bespoke antibodies to researchers within the Life Sciences discipline. CRB is continuously expanding its service portfolio to incorporate new peptide labelling options. New fluorescent dyes are incorporated frequently with current agreements in place with ThermoFisher Scientific – Molecular Probes and Licor Biosciences. The addition of DISCOVERY® Dyes to this expanding peptide dye labelling portfolio will consolidate CRB’s position as a leading player in this highly specialised field, enabling the company to synthesise more creative and complex peptide targets utilising these licence-free affordable dyes.

“We are very pleased to be able to offer this comprehensive range of generic and click reactive fluorescent dyes to our customers under this new distribution agreement” comments Emily Humphrys, Cambridge Research Biochemicals' Managing Director. “This is an important agreement for CRB, further expanding our extensive range of activated fluorescent dyes available for labelling peptides and antibodies and enabling more cost-effective scale up of dye labelled SPECTRUM™ peptides to our customers”.

Andrei Polukhtin, Fluoroprobes Managing Director added: “We’re delighted to be partnering with Cambridge Research Biochemicals to market and sell our generic and click reactive dyes in the the UK and European markets. With their extensive experience and expertise, CRB are a leader in providing dye labelled peptides to a wide range of customers and are thus ideally placed to market our dyes to the benefit of the research community”.

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About Cambridge Research Biochemicals®
Cambridge Research Biochemicals® (www.crbdiscovery.com) is a leading independent producer of custom-made peptide and antibody tools, supplying researchers in the pharmaceutical, life science and academic sectors worldwide. The primary applications of its products are as custom-made, laboratory scale reagents for proof of principal studies within early phase drug discovery and to support biomarker programmes in clinical studies. The company produces all flavours of peptides from simple to modified, stable and radio-labelled to dye labelled from milligrams to gram-scale to the highest levels of purity. In addition, CRB is a recognised expert at generating highly specific and targeted antibodies (both polyclonal and monoclonal). Fluorescent dye labelling is also a focus.

DISCOVERY Antibodies®, DISCOVERY® Dyes, DISCOVERY Peptides®, Cambridge Research Biochemicals® are registered trademarks of Cambridge Research Biochemicals Limited.

About Fluoroprobes LLC
Fluoroprobes LLC, based in Scottsdale Arizona USA, are experts in fluorescent probe synthesis and click chemistry, with years of experience manufacturing fluorescent probes, from a few milligrams to hundreds of grams. Fluoroprobes catalogue boasts the largest selection of functional groups and dyes available many of which utilise the click chemistry reaction.