About you

Key requirements for the role are significant and broad all-round laboratory experience monitoring small molecule binding and function applied to drug discovery. A good understanding of enzymology would be beneficial, as would prior use of automation equipment for liquid and compound handling used in compound profiling.

Department/Directorate Information

The Hit Discovery and Structural Design Team uses biochemical, cellular and biophysical assays to perform small-molecule high-throughput screening and fragment-based hit discovery, coupled with X-ray crystallography and electron microscopy to enable structure-based drug design within the CCDD. These methodologies are underpinned by state-of-the-art protein expression, purification and characterisation capabilities, allowing for the generation of large quantities of high-quality protein targets.