ChEMBL is a world-leading chemogenomics resource, providing open bioactivity data and associated tools to the scientific community. We have a considerable number of users from academia and industry. You will work in a team-oriented environment, collaborating closely with fellow scientists and technical experts, chemo- and bio-informaticians and software engineers across EMBL-EBI and with our many external partners from the UK and internationally. You will be responsible for the curation of biological data in the ChEMBL database. You will have excellent attention to details, strong communication skills and be able to interact with technical experts as well as scientists seeking solutions to their "real world" problems.

Reporting to the ChEMBL team leader, the job responsibilities will include:

• To curate bioactivity data in the ChEMBL database ensuring the delivery of high quality data
• To be responsible for mapping measured bioactivity data from the scientific literature to other biological entities (proteins, cell-lines etc) using a variety of bioinformatics resources and ontologies
• To be responsible for identifying and validating the potential therapeutic targets of drug molecules and compounds in clinical development from a variety of sources
• To work with data depositors to help them format and curate their data to the standards required for deposition into ChEMBL
• To manually check and annotate data by reference to the original data sources such as the scientific literature, Pharma Company pipelines and prescribing information
• To develop semi-automated processes for identifying and correcting erroneous data

While the position is envisaged as a full-time role applications for part-time working can also be considered. Please specify your preferred weekly hours/working pattern in your cover letter.

• A PhD (or equivalent) in a biological or biomedical science
• Excellent knowledge of pharmacology, potential biological targets and mechanisms of drug action
• Good knowledge of the various experimental techniques used to determine the activity of compounds in different in vitro and in vivo assay systems
• Ability to work accurately and quickly to deadlines
• Able to work both as part of a team and independently
• Good communication skills (both verbal and presentational)
• You might also have

• Prior experience of biological data curation and knowledge of bioinformatics databases
• Some knowledge of biological ontologies
• Experience of working in a drug discovery environment
• Experience of working with and manipulating file formats such as FASTA, Excel, XML, OBO and familiarity with regular expressions and text matching
• Experience of querying relational databases using SQL would also be advantageous