About the Company

T-Therapeutics is a venture-backed company on a mission to unlock the power of T cells to treat chronic and infectious diseases.
Based on technology from Professor Allan Bradley’s laboratory in Cambridge University’s Department of Medicine, T-Therapeutics has secured significant investment from a blue-chip syndicate of investors to support its drug discovery efforts and prepare candidates for clinical development.
T-Therapeutics was founded in 2022, and we are at the very beginning of our journey to develop transformative T cell derived medicines. To realise our ambition, we are currently building facilities, recruiting staff, and establishing our research operations.

Research Associate – Drug Discovery

About the Opportunity

We are seeking a motivated research associate to join our Drug Discovery team at T-Therapeutics. The team is focused on harnessing the power of T cell biology in developing novel therapeutics for treating cancer. This an excellent opportunity to contribute to the development of advanced medicines that can impact the lives of patients around the world.
In this role you will be responsible for:

Generation of expression constructs using molecular cloning techniques
Work with primary immune cell cultures and cell lines
Cell line engineering by making gene KO and overexpression
Conduct In vitro and Ex vivo cell based assays to facilitate candidate selection
Involvement in mouse model development and sample processing
Multi-parameter flow cytometry panel set up and analysis
Protein expression, purification and basic characterisation
Precise recording of daily laboratory work and
Ability to use software such as excel, Prism, flowjo and Geneious Prime DNA analysis software for data analysis and generation of high quality data for presentation

About You

Bsc or Msc degree in a relevant area (e.g. Molecular and cellular biology or relevant discipline with experience in experimental research)
Molecular biology expertise in construct designs and cloning
Strong track record in cell culture and cell line engineering
Cell biology experiences in T cell biology, hematologic cells or cancer cells is desirable
Immuno-assay techniques such as ELISA, ELISpot, flow-based assays are desirable
Experience in antibody discovery is desirable
The ability to evaluate results and communicate findings with the team to achieve desired goals
Proactive attitude and drive
Strong communication skills and the ability to work effectively as part of a team
Attention to detail and ability to multi-task
Capacity to trouble shoot
Organised and good time management

Company Benefits

T-Therapeutics offers employees a wide range of benefits. These include a generous pension contribution, life insurance, health insurance and a health cash plan. Employees will be offered share options in the company, as well as 28 days’ holiday each year (not including standard bank holidays).

You will have the opportunity to contribute to innovative drug development, in an open environment, able to learn all aspects of drug development. T-Therapeutics is also committed to enabling staff to grow professionally in a variety of ways as well as providing the chance to develop cutting-edge technologies.