Scientist, Bioanalysis and Biomarkers

Wokring within our Bioanalytical and Biomarker Development Team in the Translational Sciences Department, you will support the progression of projects through pre-clinical and clinical stages. This is a lab-based role developing and qualifying/validating bioanalytical assays either for analysing non-regulated study samples in our Cambridge facility, or for transfer and technical supervision of work conducted within contract research organisations. This is an exciting opportunity to join a team supporting projects from pre-Candidate Selection stage through to early phases of clinical trials, with scope to work on a wide range of projects at different steps of drug development.


Act as the Bioanalytical/Biomarker Lead on multi-functional Project Teams to contribute to project goals, providing direction on bioanalytical strategies and giving progress updates to key stakeholders.
Design and qualify/validate methods (e.g. PK, ADA, nAb, serum biomarkers) to support analytical strategies in line with Project goals. Carry out analyses of data to identify issues and implement necessary changes.
Share expertise within the Translational Sciences function and with other functions in a matrix environment to enhance assay development and bioanalysis activities.
Lead or contribute to technical troubleshooting with outsourced bioanalytical and biomarker assays, including but not limited to PK, ADA, serum biomarkers, flow cytometry assays.
Communicate ideas, experimental strategy, methods, and results to line manager, and present to project teams. 
Maintain an up-to-date awareness of scientific literature and competitive intelligence relevant to F-star projects.

We’re looking for someone who is adaptable, keen to learn, and enthusiastic. You’ll be organised with strong attention to detail and confident in delivering work with limited supervision. Communication skills are important along with the ability to work well within teams. This is a busy role with deadlines to meet and so you’ll be able to prioritise your workload and adapt quickly to change when needed.  



Demonstrated experience in assay development (PK, ADA and matrix biomarkers) within a biotech/biopharma/academic setting.
Minimum BSc in a relevant biological subject or equivalent qualification or demonstratable experience.
Experience with cell-based assays.
Proficient in designing and optimising immunological assays and/or biological experiments for robustness and reliable data quality, interpretation of data and trouble shooting.
Experience understanding factors affecting assay robustness and assay performance.
Excellent record-keeping and ensuring high levels of data quality.
Enthusiasm to learn and optimise new methods.
Strong communication skills and proven ability to work well in teams and independently in both face to face and virtual settings.

Experience in flow cytometry.
Experience with cell-based receptor occupancy assay.
Experience with cell-based neutralising antibody assays.
Knowledge and interest in immuno-oncology.
Experience with R programming or other programming language.

We get things done, we keep things simple and we’re driven by the science. We’re ambitious so we work hard to create an environment where we can take smart risks. We want to be innovative so encourage debate and collaboration to challenge the usual way of doing things. We love our celebrations, socialising and perks, which make F-star a fun and diverse place to work.  And most of all, everyone has the opportunity to make a difference.


Pension (8% Employer contribution)
Private Medical Insurance and Health Cash Plan
Life assurance
25days paid holiday, plus the option to buy 5 days
Travel insurance
Enhanced Maternity, Paternity, Adoption pay
Agile working opportunities
OTHER DETAILS:                              

This role is to be based in our laboratories and office space on Babraham Research Campus, South Cambridgeshire.

This is a full-time position working 37.5 hours per week. F-star is proud to fully embrace agile working which gives you options in how, where and when you get your work done, including flexible working hours and home working. 

Application Instructions: 


If you feel this role is right for you, we’d love to hear from you.

To apply, please visit our website: and upload your CV for us to view. Those that shine brightest will be contacted to discuss the role further, however, we aim to get back to everyone with a response either way.

We may choose to close the role sooner than the application closing date depending on volume of candidates and so we encourage early applications.

If, along the way, you experience any difficulties with applying via our website, please email

We aspire to be a diverse and inclusive workplace and strongly encourage suitably qualified applicants from a wide range of backgrounds to apply.

As part of our compliance in relation to the General Data Protection Regulations 2018 (GDPR) you can find our ‘Candidate Privacy Notice’ on the careers section of website.

Application Closing Date: 
28 August 2022