Never losing sight of our purpose
At Mestag we truly believe in our values and live by them every day. We’re ambitious about our science and its potential to deliver meaningful therapeutics to the patients that need them most. We believe in a culture of diversity, equality and investing in people to ensure our talented and passionate team members can fulfil their full potential.
We are based in spacious and modern laboratory and office facilities at Chesterford Research Park near Cambridge, UK – right in the very heart of the UK life science sector. Our facilities are kitted out with state-of-the-art instruments to enable our dedicated researchers to deliver incredible science.
Mestag is backed by committed leading global investors, has world-class founders and a highly experienced leadership team.
We are now transitioning our lead programme into clinic - There has never been a better time to join #TeamMestag
Job Summary/ Scope of Role
This is an outstanding new opportunity for a proactive and energetic Research Scientist/Senior Scientist to join an innovative biotech company and work closely with experienced scientists both internally and externally. We are looking for a highly collaborative cellular biologist with a passion for science who would like to join a committed, dynamic team and share our vision to bring new therapies to patients in need.
The successful candidate will provide in vitro assay expertise working closely with our talented Project Leads to independently perform cellular assays to support the transition of our lead programme into the clinic. They will undertake flow cytometry, immunohistochemistry, high content imaging and ligand (MSD, ELISA) based assays and apply troubleshooting skills as needed. This role will benefit from extensive training and exposure to cutting edge technologies.
Key Responsibilities
- Design, develop and perform complex in vitro assays to support our lead programme into the clinic using techniques such as flow cytometry, immunohistochemistry and ELISA/MSD.
- Work alongside in vivo and antibody discovery groups to achieve programme goals in a timely manner.
- Apply teamwork and adaptability to go beyond the designated scope when required to deliver project goals.
- Maintain accurate and up-to-date experimental records in electronic lab notebooks.
- Present data clearly to project teams and ensure reporting of programme progression, data readouts and status to the relevant audiences (internal and external stakeholders as required).
- Prepare reports for submission to regulatory authorities.
Minimum Qualifications and Experience Required.
- A PhD (or equivalent) in relevant area of cell biology or immunology, with significant experience in academic and/or industrial labs.
- An understanding or experience of receptor biology, tumour microenvironment and/or inflammation.
- Technical expertise in flow cytometry and/or immunohistochemistry with strong experience in developing primary/ immortalised cell-based assays.
- Ability to work in a collaborative style with colleagues and project teams within Mestag and with external partners (CROs and consultants).
- Excellent communication and presentation skills.
- Pragmatic troubleshooter able to adapt ideas and experiments to achieve key programme objectives and adhere to timelines.
Preferred, but not essential:
- Expertise in high content imaging, ELISA, MSD and complex coculture assays.
- Experience working with antibodies.
In return we can offer you
We work flexibly with a strong team spirit and offer a highly competitive total rewards package including competitive salaries, pension contributions, private medical insurance, income protection and more.
We have access to a range of onsite facilities including a gym, canteen, golf course and free on site parking.
As a team we achieve great things each day, and we take the time to celebrate successes, share and learn. We value the relationships of our close-knit team and strive to make meaningful connections in our community. We frequently hold Town Halls and team lunches, and have an active social committee, organizing regular events and ‘giving back’ activities supporting charities close to our hearts.
Feel free to have an informal discussion with us for any questions you may have, we are happy to talk to you.
About Mestag Therapeutics
Mestag harnesses new insights into fibroblast-immune interactions to develop impactful treatments for patients. We are progressing a pipeline of sophisticated first-in-class antibodies designed to improve the lives of patients with cancer and inflammatory disease. Together with our collaboration partner Janssen Biotech, Inc. we are also identifying novel targets for future therapies.
Our founding investigators comprise global experts in inflammatory disease, cancer, computational biology and fibroblast biology from the University of Oxford, Brigham & Women’s Hospital, Harvard Medical School and Cold Spring Harbor Laboratory. We are supported by leading life science investors SV Health Investors, Johnson & Johnson Innovation – JJDC, Inc., Forbion, GV (formerly Google Ventures) and Northpond Ventures.
Mestag is headquartered in Cambridge, UK, and in 2021 was recognized on the Fierce 15 list of innovative biotechnology companies.
For further information please visit our website www.mestagtherapeutics.com