Mission Therapeutics is an early-stage drug development company targeting the ubiquitin pathway for the treatment of neurodegenerative disease, rare mitochondrial diseases and fibrosis. The Company has built a leading platform for the discovery and development of first-in-class, small molecule drugs that selectively target deubiquitylating enzymes (DUBs) – an emerging drug class that is attracting significant commercial interest in the area of protein homeostasis.
We are looking for a driven, organised and proactive individual to join us at our Cambridge, UK based facilities initially on a 9 Month Fixed Term Contract. Mission Therapeutics is ideally situated on the Babraham Research Campus at the heart of Europe’s largest biotechnology cluster.
The successful applicant will be responsible for ensuring that all aspects of outsourced safety pharmacology and toxicology studies are performed to a high standard and within scheduled time frames.
Key responsibilities of the role will include:
• Act as study monitor for the design, conduct and reporting of nonclinical safety pharmacology and toxicology studies performed on behalf of Mission Therapeutics at Contract Research Organizations (CROs).
o Design nonclinical study protocols.
o Communicate and trouble-shoot issues and track/forecast activities.
o Scientific and technical review.
o Review and finalize study reports.
o Build effective partnerships with CROs.
• Study schedule management with multiple CROs in the conduct of in vitro/in vivo safety pharmacology and toxicology studies.
• Serve as point of contact to coordinate multiple CROs and ensure data quality and integrity.
• Work with other internal functional areas (e.g. DMPK, CMC, project management) in order to facilitate planning, development, tracking, and study timelines of nonclinical outsourced studies.
• Manage/track report and sub-report timelines and ensure all study reports are appropriately archived and organized.
• Provide administrative support for outsourced non-clinical studies, including integration of reported data into Mission’s internal data management system.
• Where required, participate in selection of CROs including qualification/scientific assessments and tracking of vendor performance.
Qualifications, Skills and Experience
• BSc or MSc in Toxicology or other relevant field with >2 years’ experience in the CRO/biotech/pharmaceutical industry.
• Knowledge and hands-on experience in planning, analysis and reporting of in vitro/in vivo toxicology and/or safety pharmacology studies is required. Experience as a Study Director would be an advantage.
• Strong attention to detail, with the ability to critically evaluate study-related documentation and correspondence.
• Knowledge of global regulatory guidelines (ICH/GLP/OECD) is a plus.
• Demonstrated organizational and multi-tasking skills and effective time management.
• Proficient in standard MS software (Word, Excel and Power Point).
• Strong communication skills (verbal and written) and presentation skills required.
Benefits
We offer a competitive salary along with a contributory pension scheme and other excellent benefits.
If you would like to apply for the position, please send your CV with a covering letter to hr@missiontherapeutics.com.
The closing date for applications is 31st January 2020.
In order to comply with UK employment legislation, all applicants for positions at Mission must have the right to work in the UK. In the event that a job offer is made, you will be required to provide evidence of your right to work in the UK before you commence employment with Mission.
All applications received will be managed in accordance with our Job Applicant Privacy Notice available to view on the Careers page of our website www.missiontherapeutics.com