Translational Genomics Principal Scientist (4265)

Job Overview:

To provide high quality genomic biomarker expertise for Artios’s clinical programmes and ensure the timely implementation of novel technology in the field.

Responsibilities and Duties:

Work with Translational Leads (TL’s) and Bioinformatics colleagues to oversee the implementation of genomic biomarker strategies in early phase clinical trials
Act as the key contact for Artios with CRO’s to plan, procure and implement genomic technologies
Perform evaluations of methods, platforms, new technologies and vendors for clinical genomic analysis
Ensure all processes for the delivery of high quality genomic data are in place across projects
Work with the translational and bioinformatics teams to support data QC/analysis/interpretation to report back to the project team
Provide expert genomic advice for the development of companion diagnostics
Work with the Director of Quality and TL’s to audit genomic vendors as required
To keep up to date with clinical genomics technology and be the conduit of this for the company


A PhD in Life Sciences or equivalent experience
Highly experienced in working in a clinical/translational genomics environment preferably in Pharma or Biotech
A thorough knowledge of handling and processing all types of tissues (i.e. FFPE, frozen, cfDNA, plasma) for DNA/RNA analysis from the clinic to data delivery
Experience working with and managing studies with CRO’s/3rd party laboratories
Expertise in cfDNA technology is strongly desired
An understanding of the regulatory and quality frameworks required for clinical sample processing and analysis
A sound knowledge of NGS technology available in the clinic and the related vendors
Demonstration of peer reviewed publications in the field of clinical genomics
High level of IT literacy
Excellent communication and presentation skills
Ability to work independently in an organised and methodical fashion
Good interpersonal skills working at all levels with colleagues and external CRO’s
Flexible approach to change

Application Instructions: 

This is a permanent position, offering an attractive salary & benefits package. If you have the right background, then please apply by sending your CV with a covering letter quoting Ref 4265.

In order to comply with UK Employment Law, all applicants must have the Right to Work in the UK or if from the EU, subject to receiving a relevant Skilled Worker Visa to work in the UK.

Due to the high volume of applications we receive, if you do not hear from us we will not be inviting you to interview on this occasion.

Application Closing Date: 
31 January 2023