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Aditum Bio, established by industry veterans Joe Jimenez and Mark Fishman, to fund clinical development Sosei Heptares to receive an upfront payment and strategic equity stake in Tempero Bio, plus future success-based milestone payments and tiered royalties  Tokyo, Japan and Cambridge, UK, 2 November 2020 – Sosei Group Corporation (“the Company”; TSE: 4565) has entered into an agreement1 with Tempero Bio, under which Tempero Bio has in-licensed exclusive global rights to Sosei Heptares’ mGlu5 negative allosteric modulator (NAM) program to develop therapies targeting substance use…
Cambridge, UK (November 2, 2020) — BioStrata, a specialist life science marketing and PR agency, has appointed a new senior team member to support continued and significant client growth in the United States. Jessica Grant, a B2B communications specialist with over 16 years’ experience, joins BioStrata as an Account Director based in Portland, Oregon, further building the company’s established global footprint.Jessica brings to BioStrata extensive experience in a broad mix of marketing and communications tactics across several sectors, with deep expertise in PR, content development,…
Leaders in stem cell research and cell therapy to help drive development of scalable off-the-shelf therapies for diseases with a high unmet clinical need Cambridge, UK, 02 November 2020: Mogrify Limited (Mogrify®), a UK company aiming to transform the development of ex vivo cell therapies and pioneer the field of in vivo reprogramming therapies, has expanded its Scientific Advisory Board (SAB) with the appointment of three new members. Profs. Christine Mummery, Graziella Pellegrini and Giulio Cossu will apply their experience in the transition of stem cell approaches from proof-of-concept…
WALTHAM, Mass.--(BUSINESS WIRE)--PerkinElmer, Inc. (NYSE: PKI) (“PerkinElmer”) and Horizon Discovery Group plc (LSE: HZD) (“Horizon”) are pleased to announce that they have reached an agreement on the terms of a recommended all cash offer whereby PerkinElmer will acquire Horizon for approximately $383 million (£296 million). The transaction has a total enterprise value of approximately $368 million (£284 million), is expected to close in the first quarter of 2021 subject to customary closing conditions. With this investment, PerkinElmer will expand its portfolio of leading,…
RaDaR ctDNA liquid biopsy test to be used to monitor patient response in Phase 1/2 study of MVC-101 in multiple tumor types        Research Triangle Park, NC, USA and Cambridge, UK, 29 October 2020 – Inivata, a leader in liquid biopsy, today announces a collaboration with Maverick Therapeutics (“Maverick”) for the use of Inivata’s RaDaR™ assay for the detection and monitoring of residual disease and recurrence. RaDaR will be used to monitor circulating tumor DNA (ctDNA) in patients enrolled in the Phase 1/2 study of MVC-101, Maverick’s lead program…
• Announcing the challenge This week the 7th CSP Blind Test begins - a major challenge in computational chemistry. It will see the world leading methods in Crystal Structure Prediction put to the test on real targets - with a high bar set by previous work. The 7 test systems have been sourced from leading experimentalists in industry and academia for prediction. • The importance of CSP The 3D structure and packing of crystalline materials have a big impact on their properties - this is most relevant in drug discovery and development. Small molecule drugs are usually administered in…
The DimAb™ development platform is different from traditional hybridoma fusion technologies in that it can directly isolate IgG genes from B cells of immunized animals. Using this novel platform - a number of custom development projects have already been completed with high customer satisfaction.Comparing with other animals, rabbits have a unique B cell development process that is more distant from the human development process compared to rodents. Rabbit B cells utilize a dual affinity maturation mechanism combining gene conversion and somatic hypermutation. Additionally…
Westbury, NY – Oct. 26, 2020 – BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced that it will be hosting a virtual Emerging Technologies in Diagnostics Symposium from 10 a.m. to 1 p.m. ET on Thursday, Oct. 29. “The diagnostic assay landscape is changing rapidly as the demand for faster, less expensive, more precise diagnostics continues to grow,” said Cathie G. Miller, PhD, director of product marketing, personalized medicine at BioIVT. “We wanted to take this opportunity to showcase some of the exciting new technologies that are…
London and Cambridge, October 20, 2020 - Hikma Pharmaceuticals PLC (Hikma or the Group), the multinational pharmaceutical company, and Arecor Limited, the biopharmaceutical company advancing today’s therapies to enable healthier lives, today announce they have entered into a new exclusive agreement to co-develop a ready-to-administer injectable medicine in the US through Hikma’s affiliate, Hikma Pharmaceuticals USA Inc. The agreement builds on Hikma and Arecor’s first product co-development agreement, which was announced on 9 January 2020. The product is being developed using Arecor’s…
Westbury, NY – Oct. 19, 2020 – BioIVT, a leading provider of research models and services for drug and diagnostic development, today launched its HEPATOMUNE® kit, a long-term, stable, in vitro model for evaluating immune-related and inflammation-mediated liver injury. HEPATOMUNE cultures are composed of hepatocytes, stromal cells and Kupffer cells in a tri-culture, mimicking the physiological microenvironment of the liver, and providing an optimal model for studying cytokines and cytokine modulators. Cytokines have important roles in chemically induced tissue damage repair, in cancer…