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ALAMEDA, Calif. & CAMBRIDGE, UK – October 14, 2021 – Exelixis, Inc. (Nasdaq: EXEL) and STORM Therapeutics (STORM) today announced that they have entered into an exclusive collaboration and license agreement under which the parties will discover and advance novel drug leads intended for the treatment of cancer. The collaboration will focus initially on ADAR1, advancing early work by STORM applying its proprietary RNA epigenetic platform, as well as explore an additional undisclosed target. Under the terms of the agreement, Exelixis will pay STORM an upfront fee of $17 million in exchange…
In a lengthy and complex decision reaching over 80 pages and one that will be welcomed by holders of standard essential patents (SEPs), Mr Justice Meade has given judgment in the latest in a series of trials in the UK’s Patents Court between Optis and Apple concerning Optis’ SEPs and the FRAND obligations which apply to them. Two previous trials had established that two of Optis’ SEPs were valid, essential and infringed. One of those patents had expired, the other had not. A trial is due to take place in June 2022 (“Trial E”), at which the court will decide what the terms of a global FRAND…
The International Energy Agency (IEA) released its World Energy Outlook 2021 (WEO-2021) on 13 October 2021. As widely predicted, 2021 saw a large rebound in coil and oil use resulting in the second-largest annual increase in CO2 emissions in history. While financial commitments have been made towards reaching the IEA’s Net Zero Emissions 2050 scenario, public spending on sustainable energy has only mobilized an estimated one-third of the required investment. The WEO-2021 highlights four key measures that can close the gap between current pledges and those required to meet the targeted…
RoslinCT developing life-changing gene and cell therapies in Edinburgh’s BioQuarter-Company has doubled its workforce in the last year and plans 25% more jobs by end of 2021 A new state-of-the-art cell and gene therapy manufacturing facility in Edinburgh has been formally opened by Ian McCubbin CBE on behalf of Sir Patrick Vallance, the Chief Scientific Adviser to the UK government. The building – which is called the BioCube – is an additional home to RoslinCT, one of the world’s leading manufacturers of human cell and gene therapies, which works with clients to develop and manufacture life-…
Babraham, 07 October 2021: Babraham Research Campus Ltd, which develops and manages the Babraham Research Campus, and the Babraham Institute have secured funding for fifteen PhD studentships from UKRI-BBSRCas part of a Collaborative Training Partnership (CTP). Through a tailored programme of skills training and scientific and industry supervision the partnership will produce a cohort of bioscience researchers equipped with excellent research skills and commercial know-how. Campus CTP projects combine scientific and industry supervision to train PhD students…
AMSBIO have supplied custom Chimeric antigen receptor (CAR)-T products to the University of Strathclyde (UoS) in Glasgow, UK, and ScreenIn3D Ltd, allowing them to perform novel immune-oncology assays in 3D microfluidic cancer models.CAR-T cells are genetically modified T-cells used to find and kill cancer cells by targeting specific cancer-associated proteins, or antigens. CAR-T cell therapy is highly effective against haematological malignancies, but faces challenges in solid tumours due to the immunosuppressive effects of the tumour microenvironment. Often, combination therapies, such…
Click here to view the October 2021 edition of eNews
Marcel Kuiper has recently joined CPI as a Business Development Manager - Outreach. Marcel joins CPI from KTN where he was a Knowledge Transfer Manager in the Health Team. He is based in Cambridgeshire in order to engage SMEs in the Cambridge and Peterborough Combined Authority (CPCA) Region which could benefit from a new ERDF Project, SPRINT (Supporting Process Innovation for Novel Therapies). SPRINT aims to support and accelerate the commercialisation of novel biological therapeutics as well as equipment and processes supporting these therapies. Please contact Marcel (marcel.kuiper@uk-cpi.…
Cambridge, UK, 05 October 2021: CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the commercial launch of its Oncology Service in response to the global need to improve cancer drug discovery approval rates. Understanding the relationship between pharmacokinetics, pharmacodynamics (PK/PD) and efficacy is critical to the successful development of new medicines, but at present this relationship is primarily investigated using animal models – a process that is time-consuming, ethically…
Cambridge, UK, 05 October 2021: Mogrify Limited (Mogrify®), a biopharmaceutical company pioneering the development of a new class of in vivo reprogramming therapies and transforming the development of ex vivo cell therapies, today announced the appointment of Dr. Louise Modis as Chief Scientific Officer, following the recent completion of a $33 million USD Series A funding. Louise is an accomplished scientific leader in therapeutic discovery and development, and holds considerable experience in the progression of pre-clinical and clinical-stage assets, across various modalities and…