Location: Hatfield, Hertfordshire, UK
Position Type: Full-time
Seniority: Senior Scientist / Principal Scientist (based on experience)
Salary: Competitive, dependent on experience
Application Deadline: 25 August 2025
Please send your resume to: [email protected]
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About Pharmidex:
Pharmidex is a respected, science-led, MHRA-accredited, GLP-compliant, AAALAC approved, preclinical CRO based in the UK. Pharmidex offers integrated in vitro ADME, bioanalysis, in vivo pharmacology, and discovery DMPK services supporting global start-ups, biotech, pharmaceutical and non-profit organisations. We are and have supported drug discovery and development for over two decades, conducting more than 16,000 studies to date contributing to more than seventeen drugs at various stages of clinical development.
With an expanding portfolio across Respiratory, Oncology, CNS, Metabolic and Immunological diseases, we are growing our preclinical teams to meet increasing demand for high-quality, translational studies. From early PK screening to regulatory bioanalysis, we offer flexible, high-quality scientific support tailored to our clients’ needs.
At Pharmidex, we are passionate about advancing new therapies and improving human health. Our mission is driven by excellent science, a commitment to quality, and a collaborative spirit that runs through everything we do.
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Job Summary:
This is an exciting opportunity for a motivated Senior or Principal Scientist to lead the establishment and execution of innovative translational preclinical models, contribute to client success, and shape the future of preclinical research at Pharmidex. Opportunities are available on both a permanent and part-time basis, offering flexibility for the right candidates.
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Key Responsibilities:
• Take a lead role in establishing, developing, and validating preclinical models in-house – with a focus on respiratory disease, oncology, and infection.
• Serve as Study Director, managing studies from planning and execution through to data reporting and scientific interpretation.
• Coordinate and maintain a safe, compliant, and well-organised laboratory environment.
• Support and supervise technical staff across all preclinical projects.
• Engage with clients and collaborators to ensure successful delivery of studies and ongoing relationships.
• Contribute to internal project reviews, innovation initiatives, and cross-functional discussions.
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Your Background:
• Degree (BSc/MSc/PhD) in Biological Sciences, Pharmacology, or a related life sciences discipline.
• Minimum 3 - 5 years of hands-on preclinical experience in a pharma, biotech, or academic translational research setting.
• Demonstrable experience in developing and running preclinical Respiratory or Oncology models.
• Hold or have previously held a Home Office Personal Licence (PIL Modules 1–3 or equivalent).
• Proven ability to work in multi-disciplinary teams and independently manage projects.
• Familiarity with preclinical techniques including multiple administration routes.
• Competent in data analysis using GraphPad Prism, SPSS, or similar software.
• Experience of managing large and complex studies with good documentation and planning skills.
• Flexible and willing to conduct occasional out-of-hours work to meet study needs.
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Desirable (not essential):
• Experience with preclinical imaging techniques (e.g. IVIS, microCT).
• Practical expertise in cell culture or ex-vivo sample analysis.
• Background in GLP or regulatory-aligned studies.
• Previous exposure to client-facing roles or project oversight in a CRO setting.
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Why Join Pharmidex? For over 20 years, Pharmidex scientists and staff have worked side-by-side with our clients to support the discovery and development of novel therapeutics. When you join Pharmidex, you become part of a team committed to making a real difference in global health through innovative science, operational excellence, and client-focused delivery. Whether your background is in life sciences, operations, administration, or beyond, your contribution is key to advancing new medicines and shaping the future of Pharmidex. In return, we offer a collaborative and supportive environment where your career can thrive.
Key benefits include:
• Opportunity to work on diverse and impactful preclinical studies.
• Be part of a growing team where your expertise will help shape model development and client delivery.
• Flexible and collaborative culture with exposure to cross-disciplinary science.
• Career development aligned with company growth.
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What We Offer:
•Competitive salary based on experience.
•Defined career development path with mentorship and training support.
•Company pension scheme with employer contribution.
•Life insurance (4x annual salary).
•Employee rewards and discounts platform.
•Free onsite parking and subsidised staff canteen.
•Opportunities to volunteer and contribute to social impact projects.
•Being part of a purpose-driven company that works with over three hundred clients. globally, including top pharma and emerging biotech’s.