The Rosalind Franklin Institute (the Franklin) is a technology institute established by the UK Government as a unique centre committed to advancing tools that are needed to transform healthcare in the future.

The Institute brings together researchers in life and physical sciences, and engineering, to develop a spectrum of tools which we will use to image, interpret and intervene in biological systems. These insights will speed up the discovery of new medicines, help find new diagnostics and contribute to a deeper understanding of human health and disease. Our Science Strategy seeks to focus the Franklin’s research and unite our researchers around our Technology Innovation Challenges and Life Science Challenges. For more information on the Franklin’s Challenges click here.

The Role

We are seeking a highly motivated Research Assistant to support cutting-edge research in cell-cell interaction in epithelia. The role will focus on the development and genetic modification of human gut organoid and cell models, including the generation of fluorescently tagged proteins and disease-relevant phenotypes. The role will involve apply molecular biology techniques including DNA cloning, qPCR, and sequencing, CRISPR/Cas9 genome editing, advanced 2D and 3D cell culture, and fluorescence imaging techniques including super resolution. The post-holder will handle human tissue samples in compliance with HTA regulations and prepare growth factors for organoid maintenance.

The successful candidate will support a collaborative, multidisciplinary research environment.