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Who we are:   

Life, Reimagined    

Constructive Bio is a VC-backed biotechnology startup based in Whittlesford, Cambridge. Our unique technology turns living cells into biofactories, creating sustainable new materials and therapeutics. With full control of the genetic sequence and code, we are exploring chemical space previously unreached by natural biology.  

Constructive Bio is a spinout from Professor Jason Chin's laboratory at the MRC Laboratory of Molecular Biology in Cambridge. Learn more about the Chin lab achievements here: https://www2.mrc-lmb.cam.ac.uk/ccsb/jason-chin/   

We secured $58 million Series A fundraising. Read more here: https://www.constructive.bio/blog/news/constructive-bio-secures-58-million-in-series-a-financing   

What we’re looking for:  

The jobholder will be a key member of the Therapeutics Discovery team. As this is a technical lab-based role, they will be responsible for developing novel biotherapeutics based on Constructive Bio’s proprietary platform technologies. The successful candidate will leverage their expertise in molecular biology, protein expression and purification, and functional analysis to drive projects from conception to commercially relevant endpoints. They will design and implement discovery and development projects to generate therapeutic candidates containing non-canonical amino acids (ncAAs), enabling novel capabilities and mechanisms of action for commercial applications. In addition, they will also be expected to contribute to continuous improvement projects or other core activities beyond discover and development within Constructive Bio.

For the full job spec, click here. 

Application Instructions:
Application Closing Date:
12 December 2025
Salary:
Competitive