A recent study published in the Journal of Pharmaceutical Sciences (https://doi.org/10.1016/j.xphs.2024.10.013) analysed the complexities of three-dimensional crystal packing arrangements of small-molecule drug candidates, focusing on the CCDC Solid Form Health Check to assess the risk of thermodynamically stable solid forms during drug development.

In this webinar, Shubham  Sharma, a computational materials scientist at Pfizer, will present a combined approach using experiments, informatics, and energetic calculations that analysed four competing polymorphs of a myeloperoxidase (MPO) inhibitor.

This comprehensive method enhanced the understanding of solid form structures, properties, and performance, facilitating effective derisking and selection of solid forms.

Who should attend:
- Pharma manufacturing
- Solid Form and Computational Scientists
- Drug Development and Discovery Scientists