Amsbio has launched over a range of over 30 independently developed and manufactured organoid culture-related cytokines for researchers working with stem cells and induced pluripotent stem cells (iPSCs). This new range of cytokines is tailored for and validated in organoid culture, ensuring high compatibility and making your research more controlled and reproducible.

In a growing number of research areas, organoids have become a key cell culture tool, widely applied in development and disease modelling, precision medicine, toxicology studies, and regenerative medicine.

Available cytokines for organoid culture include Activin A, BMP-4, EGF, FGF-4, FGF-10, FGFb, FGF8b, HGF, IGF1, Noggin, R-Spondin 1, Shh, and Wnt3a. These cytokines feature endotoxin levels as low as ＜0.01 EU/μg and are characterized by high activity, high purity, and high lot-to-lot consistency.

Supplied as ready-to-use formulations, these products are extremely easy-to-use following simple and convenient protocols. Beneficially, each cytokine for organoid culture kit is highly effective at preserving the structural and genetic characteristics of normal mammalian tissues, maintaining the heterogeneity of the original tissue. Using these products, high quality organoids can routinely successfully be cultivated within just 4-7 days.

All cytokines supplied by Amsbio have been validated in in vitro models, including human tumor organoids such as pituitary adenoma organoids and breast cancer organoids; human normal organoids such as iPSC-derived intestinal organoids as well as mouse normal organoids such as intestinal and pancreas organoids.

For further information please visit https://www.amsbio.com or contact Amsbio on +31-72-8080244 / +44-1235-828200 / +1-617-945-5033 / [email protected].

Now part of the Europa Biosite group of companies, AMS Biotechnology (Amsbio) is recognized as a leading transatlantic company contributing to the acceleration of discovery through the provision of cutting-edge life science technology, products, and services for R&D in the medical, nutrition, cosmetics, and energy industries. Amsbio has in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion, and proliferation. This expertise in cell culture and the ECM allows Amsbio to partner with clients in tailoring cell systems to enhance organoid and spheroid screening outcomes using a variety of 3D culture systems, including organ-on-a-chip microfluidics. For drug discovery research, Amsbio offers assays, recombinant proteins, and cell lines. Drawing upon a huge and comprehensive biorepository, Amsbio is widely recognized as a leading provider of high-quality tissue specimens (including custom procurement) from both human and animal tissues. The company provides unique clinical grade products for stem cells and cell therapy applications. This includes GMP cryopreservation technology, and high-quality solutions for viral delivery.