In-vivo Biologist, Oncology
Research Scientist 2/Senior Research Scientist depending on experience

Role Summary

New Path Molecular is a spin out from the group of Prof Steve Ley at the University of Cambridge. We are looking for an in-vivo biologist to join our drug discovery team in Cambridge working as part of our research into phosphatidylserine binding protein drug conjugates as a pan-tumour approach for the treatment of cancer. We’re looking for someone who has a passion for research and drug discovery and can offer the right person a challenging role in a dynamic small company at the forefront of innovation and the chance to work with world leading scientists through our collaborations with industry and academia.

Key Responsibilities:

• Design and execution of animal studies in oncology in a variety of different models including cell line xenograft and patient derived xenografts.
• Design and execution of animal studies for pharmacokinetic and toxicological readouts for clinical candidates.
• Liaising with CROs to design, schedule and project manage studies
• Writing of study reports and documentation including health and safety documentation.
• Liaise with the CTO and other colleagues to progress projects effectively
• Maintain accurate records of experimental work
• Assist with production of reports and presentations
• Assist in the safe running of the laboratory
• Assist with the efficient running of the research laboratory including ordering, management, storage and disposal of chemicals and consumables
• Continually update knowledge and understanding in field or specialism
• Translate knowledge of advances in the subject areas into research activity

Person Profile

Education & qualifications

The candidate must have a BSc Hons in biology and a PhD (or equivalent industrial research experience).

Specialist knowledge & skills

The role holder would possess research experience, either academic or industrial with sufficient breadth/depth of specialist knowledge in the discipline and of research methods and techniques to work as a biology lead in an established research programme including experience in:
• Cancer biology
• Oncology translational models to show efficacy, PK and mechanism of action for biological molecules in animal studies
• Cell culture
• Project management
Experience in the following would be an advantage but not essential:
• Flow cytometry
• Confocal microscopy
• Basic histopathology and IHC
• Organoid models
• Protein-drug conjugate biology
• Assay development
• In-vitro cell-based assays to profile compounds

Interpersonal & communication skills

Self-motivation, team player and strong communication skills

Location: Babraham Research Campus, Cambridge UK
The Babraham Research Campus is considered to be one of the UK’s leading campus' to support early-stage bioscience enterprise and is distinct in its co-location of bioscience companies with the Babraham Institute. World class research and business come together to promote innovation and strengthen links between academia and the commercial world. For more information see https://www.babraham.com/

Working pattern: Monday – Friday
Hours of work: fulltime (although candidates wishing to work part time will also be considered)
Length of appointment: permanent
Probation period: 3 months
Annual leave: 20 days plus public holidays
Pension eligibility: New Path Molecular Pension Scheme

Pre-employment Check Requirements

We have a legal responsibility to ensure that you have the right to work in the UK before you can start working for us. If you do not have the right to work in the UK already, any offer of employment we make to you will be conditional upon you gaining it.

Equal Opportunities

We are committed to a proactive approach to equality, which includes supporting and encouraging all underrepresented groups, promoting an inclusive culture and valuing diversity. We make selection decisions based on personal merit and an objective assessment against the criteria required for the post. We do not treat job applicants or members of staff less favourably than one another on the grounds of sex (including gender reassignment), marital or parental status, race, ethnic or national origin, colour, disability (including HIV status), sexual orientation, religion, age or socio-economic factors.