October 2021

Guest blog by Charles Richmond, F-Institute

Guest blog by Joanne Ward, Chief Operations Officer, NF2 Biosolutions UK

I haven’t written a blog before but have shared my story in case it helps others along on their journey.  They say sharing your story of how you overcome things is someone else’s survival guide!

What is a cytokine storm? 

Cytokine Release Syndrome (CRS), otherwise known as cytokine storm, is a systemic inflammatory response caused by complications due to disease, infection or an adverse effect of biologic therapy. The clinical symptoms of a cytokine storm are massive release of a potent cocktail of pro-inflammatory cytokines into the general circulatory system, leading to severe multi-organ damage, failure or potentially death. This is an extremely unwanted immunotoxicological side effect in drug development.