Cambridge, UK, and New York City, USA, 11 February 2021: Artios Pharma Limited (“Artios”), a leading DNA Damage Response (DDR) company developing a broad pipeline of precision medicines for the treatment of cancer, today announced the start of a clinical trial of its small-molecule ATR inhibitor, ART0380, in patients with advanced or metastatic solid tumors. ART0380 was originally in-licensed from The University of Texas MD Anderson Cancer Center and ShangPharma Innovation in 2019.  The molecule was jointly developed as part of a collaboration between ShangPharma and MD Anderson’s…

Quotient Sciences, the drug development and manufacturing accelerator, announced that it has acquired Arcinova, the U.K.-based multiservice contract development and manufacturing organization (CDMO). With over 40 years of experience and 160 employees, Arcinova provides drug substance, drug product and bioanalysis services to over 200 pharma and biotech customers worldwide. The acquisition expands Quotient’s service portfolio and will enable the integration of drug substance, drug product and clinical testing capabilities all under one organization — extending the 12-month drug development…

Cambridge, UK, 09 February 2021: Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research and drug discovery company, today announced the appointment of John Montana, PhD, as a Non-Executive Director. Expansion of the Board of Directors will support the Company’s further growth. Dr Montana brings over 30 years’ drug discovery and development experience across the pharmaceutical, biotech, and contract research sectors. Dr Montana is currently Operating Partner at Forbion, the life science venture capital firm. His previous roles have included Corporate Vice…

“The programme has been specially designed to support MedTech, Diagnostic and Digital Health, including service delivery, ventures to successfully engage investors needed to support their future growth, commercialise scientific discovery and solve global health and environmental challenges. If the last twelve months have taught us anything it is that solutions to many of our current problems are within the hands of the scientific community. Our ultimate aim is to help them make sure those solutions make it out of the lab and into the world”.   Richard Hebdon, Innovate UK’s Interim Deputy…

Research Triangle Park, NC, USA and Cambridge, UK, 4 February 2021 -- Inivata, a leader in liquid biopsy, today announces it has raised $35 million (£25.7 million) in a second close of a Series C financing round. The round was led by Soleus Capital, who were joined by new investors including Janus Henderson Investors and Farallon Capital alongside existing investor IP Group. This latest funding takes the total raised in the Series C to $60 million and follows the $25 million invested by NeoGenomics, Inc (NASDAQ: NEO) in 2020, alongside the formation of a strategic collaboration with Inivata.…

Cambridge, United Kingdom – 3 February 2021 - Congenica, the digital health company enabling rapid and accurate analysis of complex genomic data to transform people’s lives, announces a collaboration with Gabriel Precision Oncology Limited (“Gabriel”), a spin-out company from the University of Glasgow. Working together, Congenica and Gabriel will develop a highly automated somatic cancer clinical interpretation software platform, which will support the use of multiple genomic assays in routine clinical practice to enable NGS-based cancer molecular diagnostics at scale. Through this…

Ion channels represent a large but under-exploited class of drug targets beyond G protein-coupled receptors (GPCRs) Collaboration combines Sosei Heptares’ leading structure-based drug design platform with Metrion Biosciences’ ion channel expertise Joint drug discovery program to focus on a single ion channel that is a well-validated target for neurological diseases   Cambridge, UK and Tokyo, Japan, 01 February 2021– Metrion Biosciences Limited (“Metrion”), the specialist ion channel CRO and drug discovery company and Sosei Group Corporation (“the Company”; TSE: 4565), the…

AMSBIO has expanded its range of primary human cancer cells sourced from a wide variety of tissue types that allow the study of cancer in a more in vivo like fashion.Many scientists acknowledge that using immortalized cell lines as surrogates offers only a poor reflection of the diverse profiles of real cancer tumors. During long-term culture, immortalized cells adapt to their <I style="mso-bidi-font-style: normal">in vitro environment, and often mask or lose the in vivo phenotypic events being studied – in addition to hiding key epigenetic or immunotherapy markers. These shortfalls…

The deadline for compliance with the EU Medical Device Regulations is looming. On the 25th of May 2017, new EU regulations for medical devices and in vitro diagnostic medical devices entered into force, giving medical device companies a 3 / 5 - year transition period to achieve compliance. Whilst the MDR has been delayed as a result of the COVID-19 pandemic, by May 2021 medical devices must adhere to the updated regulations, transitioning from the Medical Device Directive (MDD) to the Medical Device Regulations (MDR). The implementation of the In Vitro Diagnostic Regulations (IVDR) follows…

UPPSALA, Sweden, February 2, 2021 - LINK Medical, the Northern European clinical research organization (CRO), and the Swedish women’s health company Gedea Biotech announced today that it has enrolled the first patient in the NEFERTITI clinical study of its lead product, pHyph, a vaginal tablet for topical treatment of bacterial vaginosis (BV). The randomized double-blind placebo-controlled study is designed to confirm safety and efficacy of pHyph and is coordinated by Nottingham University NHS Hospitals Trust in the UK and LINK Medical. Bacterial vaginosis is a vaginal infection with a…