AMSBIO has added new experimental cell lines to its CAR T cell research range. Recent FDA approval of CAR T cells for treatment of leukemia and lymphoma has resulted in rapid growth in research on the therapeutic uses of such cells. The new AMSBIO experimental cell lines provide you with the power to screen antibodies and ligands against your target, enhancing your search for new CAR T therapies.A therapeutic Chimeric Antigen Receptor (CAR) is a transmembrane protein designed with an extracellular domain based on an antibody single-chain variable fragment (scFv) and…
The AMR Centre has today welcomed the UK Government’s announcement of a new plan to cut inappropriate use of antibiotics and reduce drug resistant infections.
The national action plan, announced by Health Secretary Matt Hancock at the World Economic Forum in Davos, sets out how the UK will achieve its new 20 year vision for a world in which AMR is contained and controlled by 2040, covering health, animals, the environment and the food chain.
Key to the plan is the launch of a trial by the National Institute of Health and Care Excellence (NICE) and NHS England to develop a new payment model…
Arecor Limited, the specialty pharmaceutical company leveraging its innovative and proprietary formulation technology to develop superior treatments for a range of disease areas, including diabetes, is pleased to announce that a feature profile by the highly regarded industry publication, SCRIP, is now available on the news section of the company’s website via the following link: http://arecor.com/news/
This excellent feature came out shortly after the Company announced that it had filed a Clinical Trial Application (“CTA”) to conduct a Phase I study in Diabetes Type 1 patients of its ultra-…
Cambridge, UK, 21 January, 2019: Horizon Discovery Group plc (LSE: HZD) (“Horizon” or “the Company”), a global leader in gene editing and gene modulation technologies, today announced the extension of its CRISPR Screening Service to include ex vivo T lymphocytes. The service extension meets the requirements of immunology-based research in drug discovery, enabling new gene targets to be identified in biologically and potentially therapeutically relevant settings.
CRISPR screens in primary T lymphocytes have proved challenging, owing to complex issues around the introduction of the screening…
Cambridge, UK, 22 January: PredictImmune, developers of pioneering prognostic tools for guiding treatment options and improving patient outcomes in immune-mediated diseases, today confirmed its latest patent grant in Canada. The Canadian patent is part of PredictImmune’s first family of intellectual property relating to methods for predicting autoimmune disease risk and follows successful grants in the UK and Europe in October 2018.
The Canadian, UK and European patents are part of an expanding and comprehensive portfolio of patent applications and other intellectual property supporting…
CAMBRIDGE, UK, 14 January 2019 – EVONETIX LTD (‘Evonetix’), the Cambridge-based company pioneering an innovative approach to scalable and high-fidelity gene synthesis, today announced it has appointed Stephanie Brooking as Head of Product Management. Evonetix aims to utilise its innovative silicon chip approach to deliver a high-throughput solution for the synthesis and assembly of DNA molecules with high fidelity. Stephanie will help to define the Company’s strategy for market entry and longer-term product marketing for its novel gene synthesis products.
Stephanie has over 20 years’…
Aptamer Group today announced it has signed an agreement with AstraZeneca to explore the potential of using aptamer technology to target the kidney. The two-year agreement will give AstraZeneca use of Aptamer Group’s proprietary technology to explore the feasibility of developing the next generation of drug delivery vehicles, called Aptamer Drug Conjugates (ApDCs).
Aptamers are oligonucleotide or peptide molecules that bind to a specific target molecule. They are emerging as promising therapeutic agents. Their ability to fold into distinct secondary or tertiary structures gives them high…
Cambridge and Farnborough, UK, 15 January 2019: Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, and Peak Analysis and Automation (PAA), a leader in the industry for the design and manufacture of automated laboratory equipment, will collaborate to offer automated micro-plate handling capabilities for single cell analysis. PAA's S-LAB™ plate handler will be integrated with Sphere Fluidics’ Cyto-Mine® Single Cell Analysis System to help increase throughput in antibody discovery and cell line development.
Sphere Fluidics…
Wickham Laboratories are excited to announce their most recent publication on “The Importance of Testing for Pyrogens in Raw and In-Process Materials”, written by Section Head of Endotoxin and Cytotoxicity Testing, Sophie Bell.
The article, published by International Biopharmaceutical Industry (IBI) in their December issue, discusses the effects pyrogens can have on humans and focuses on the three different methods used to test for pyrogens as well as why such testing is compulsory within the pharmaceutical and medical device industry.
An excerpt of this article as follows:
Pyrogens are…