Role Summary

Based in our Discovery Centre on the Cambridge Addenbrookes campus, this Senior Scientist role sits at the heart of Genetic Toxicology, working alongside colleagues in Clinical Pharmacology and Safety Sciences to advance the genotoxicity assessment of new medicines. The position focuses on high-throughput imaging and screening methodologies to generate robust, decision-enabling data that informs safety assessment across drug discovery and development.

Domainex is a leading drug discovery service company located near Cambridge, UK, serving clients across the pharmaceutical, biotechnology, academic, and non-profit sectors worldwide. With a track record of delivering an average of one drug candidate per year over the last six years, Domainex consistently provides high-quality, efficient, and innovative scientific solutions.

Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development.