Time: 10 AM EST | December 11, 2025
Interferon-gamma (IFNγ) plays a paradoxical role in CAR-T therapy—it’s essential for antitumor activity but can also limit CAR-T expansion and persistence, especially in CD28-based designs.
Time: 10 AM EST | November 24, 2025
CAR-T therapy has achieved remarkable success in hematologic malignancies but faces major hurdles in solid tumors due to their immunosuppressive microenvironment. Angiogenesis, driven by the VEGF pathway, plays a critical role in fueling tumor growth and suppressing immune responses.
LONDON, UK & COPENHAGEN, Denmark – November 4, 2025 – Coulter Partners, the global expert building leadership teams for Health, Science and Technology innovation businesses, successfully completed a search assignment for Vicore Pharma Holding AB (STO: VICO) and is pleased to announce the placement of Katrine Husum as R&D Senior Project Director.
Your group
The Cortes-Ciriano group studies the mutational processes and mechanisms of genome instability
underpinning tumourigenesis, immune escape, and drug response through the analysis of high-throughput sequencing data from clinical samples. The group is also leading the development of novel approaches for early cancer detection using long-read sequencing. More information about the group can be found here.
Your supervisor
Labs using AI in their supply chains are seeing serious gains. Think a 35% reduction in inventory levels, 15% lower logistics costs, and $300 million in savings by predicting stock risks before they happen. The secret? Smart automation.
Artificial intelligence (AI) is transforming how life science labs manage procurement, from forecasting inventory needs to streamlining vendor selection. Tasks that once required hours of manual effort, like comparing prices, coordinating orders, and pulling spend information, can now be done in minutes.
Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenges.
We have an exciting opportunity for a Head of Science and Innovation to help shape the future direction of one of the world’s leading cancer genomics resources. You’ll join a diverse, multidisciplinary team working at the cutting edge of data and discovery where collaboration, innovation, and inclusion is central to everything we do.
At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No.
The October edition of our People Pathways newsletter is now available to read here!
Featuring:
✅ Preview of One Nucleus 2026 courses
✅ One Nucleus Jobs Board - Helping the Industry
✅ Online Training in Python Programming, Data Science, Networks, Machine Learning & AI
and some useful information...